Burtscher, J. & Burtscher, M J. Sport Heal. Sci. 13, 761–763 (2024).
This paper explores the relationship between physical exercise and brain health in older adults. Aging is associated with declines in cellular, tissue, and systemic functions, leading to cognitive decline and increased vulnerability to diseases like dementia.
Regular exercise can counteract aging effects by improving cellular stress responses, mitochondrial functions, and waste-disposal efficiency. Contrary to old beliefs, exercise remains beneficial even at older ages, preserving muscle mass, cardiorespiratory fitness (CRF), and cognitive function. CRF, a measure of endurance exercise performance, is crucial for functional independence and quality of life.
The paper highlights the emerging concept of the “muscle-brain axis,” where myokines released by skeletal muscles during exercise play a significant role in brain health. The myokine irisin, in particular, has been noted for its potential cognitive benefits.
Overall, the paper underscores the importance of maintaining physical activity to promote both physical and mental health in aging populations.